NLRP7 ve NLRP7’nin İmmün Ayrıcalık ve Toleranstaki Fonksiyonları
Summary:
Assigned to: Aybüke Garipcan, Gizem Olay Artık
NLRP13’ün Translasyon Sonrasındaki Kesilimi ve Bu Kesilimin NLRP13’ün Aktivasyonuna Olan Etkileri
Summary: Involment of NLRP13 in inflammation has been investigated via using several cytokine/chemokine arrays, elisa and western blotting. In addition, the effects of post-translational modifications on NLRP13 protein activity has been studied through enzymatic assays.
Assigned to: Açelya Yılmazer
ASC Zerrelerinin Antijen Sunumunda Görevli Araçlar Olarak in vivo Çalışmaları
Summary:
Assigned to: Mesut Berber, Aylin Alkan
ASC Zerrelerinin Polimerizasyon Dinamikleri ve Bölgeleri
Summary: The ASC speck structurally resembles aggresomes, though formation is rapid and requires pro-inflammatory signals, and is based on specific homophilic interactions by PYD and CARD separately. We aim to observe and investigate interaction types and strengths between surfaces of ASC constructs using atomic force microscopy.
Assigned to: Hasan Ozan Otaş