ARAŞTIRMA KONULARI
NLRP7 ve NLRP7’nin İmmün Ayrıcalık ve Toleranstaki Fonksiyonları
Assigned to: Aybüke Garipcan, Gizem Olay
NLRP13’ün Translasyon Sonrasındaki Kesilimi ve Aktivasyon Üzerine Etkileri
Involvement of NLRP13 in inflammation has been investigated using cytokine/chemokine arrays, ELISA, and western blotting. Additionally, the effects of post-translational modifications on NLRP13 activity have been analyzed through enzymatic assays.
Assigned to: Açelya Yılmazer
ASC Zerrelerinin Antijen Sunumunda Görevli Araçlar Olarak in vivo Çalışmaları
Assigned to: Mesut Berber, Aylin Alkan
ASC Zerrelerinin Polimerizasyon Dinamikleri ve Bölgeleri
The ASC speck structurally resembles aggresomes; however, its formation is rapid, requires pro-inflammatory signals, and depends on homophilic PYD and CARD interactions. This project aims to investigate interaction types and strengths using atomic force microscopy.
Assigned to: Hasan Ozan Otaş
